DEVELOPMENT OF A NOVEL NS1 COMPETITIVE ENZYME-LINKED IMMUNOSORBENT ASSAY FOR THE EARLY DETECTION OF ZIKA VIRUS INFECTION.

Development of a novel NS1 competitive enzyme-linked immunosorbent assay for the early detection of Zika virus infection.

Zika virus (ZIKV) is a flavivirus that has emerged as a global health threat after the 2015 outbreak in the Americas, where devastating congenital defects were documented.There are currently no vaccines to prevent ZIKV infections nor commercially available clinical diagnostic tests demonstrated to identify ZIKV without cross-reactive interference o

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Noninvasive and quantitative measurement of C4d deposition for the diagnosis of antibody-mediated cardiac allograft rejectionResearch in context

Background: C4d is a specific biomarker for the diagnosis of antibody-mediated rejection (AMR) after cardiac transplantation.Although strongly recommended, routine C4d surveillance is hindered by the invasive nature of endomyocardial biopsy.Targeted ultrasound (US) has high read more sensitivity, and C4d is abundantly expressed within the graft of

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